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Facile,single-pot preparation of nanoporous SiO2 particles (carrier) with AgNPs at core and crust for controlled disinfectant release
Authors:M. Salman Haider  Godlisten Shao  Ayyaz Ahmad  S. Muhammad Imran  Nadir Abbas  Ghulam Abbas  Manwar Hussain  Hee Taik Kim
Affiliation:1. Applied Science Research Institute, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea;2. Department of Chemical Engineering, University of Gujrat, HH Campus, 50700 Gujrat, Pakistan;3. Department of Chemical Engineering, Hanyang University, 1271 Sa 3-dong, Sangnok-gu, Ansan-si, Gyeonggi-do 426-791, Republic of Korea;4. Department of Chemical Engineering, Muhammad Nawaz Sharif University of Engineering and Technology, Multan, Pakistan;5. Department of Chemical Engineering, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan;6. Department of Chemical Engineering, University of Hai’l, Hai’l, Saudi Arabia;7. Department of Chemistry, Mkwawa College, University of Dar es Salaam, P.O. Box 2513 Iringa, Tanzania
Abstract:This study demonstrates a novel, facile and one-pot approach to synthesize silica nanoparticles with silver at core and crust (SiNP-AgCC). A modified Stöber method was used to make SiNP-AgCC. A significant reduction in the size of SiO2 nanoparticles was seen, with 2–5 nm AgNPs being uniformly distributed on the surface and 10–20 nm AgNPs in the center. A typical mesoporous SiO2 particle (SiNP) produced using the Stöber method was transformed to nanoporous SiO2 by this modified Stöber method. Nanoporous SiO2 particles with silver in the center are advantageous for slow and consistent Ag+ release, which was confirmed by Ag+ ion release test. Antibacterial activities of the samples were tested to evaluate the disinfection performance of the samples on gram-negative bacteria (Escherichia coli) using disk diffusion and the LB-agar method. SiNP-AgCC showed prolonged silver release for more than 20 days and improved antibacterial properties even after five days of incubation.
Keywords:Corresponding author at: Applied Science Research Institute, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.  Modified Stöber method  Silver release  Antibacterial properties
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