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Microwaves-assisted solvent-free synthesis of N-acetamides by amidation or aminolysis
Authors:Clotilde Ferroud  Marie Godart  Stéphane Ung  Hélène Borderies  Alain Guy
Institution:Conservatoire National des Arts et Métiers, Laboratoire de Transformations Chimiques et Pharmaceutiques, UMR CNRS 7084, Case 303, 2 rue Conté, 75003 Paris, France
Abstract:The preparation of acetamides directly from amines and an acetyl donor under microwaves without any catalyst is described. The inexpensive, solvent free, and fast reaction conditions are the important features of this procedure.
Keywords:Acetamides  Solvent-free conditions  Microwave-assisted synthesis  Regiocontrol
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