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Convergent synthesis of the A-E ring segment of ciguatoxin CTX3C
Authors:Isao Kadota  Takashi Abe  Hiroyoshi Takamura
Institution:a Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan
b Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan
Abstract:A convergent synthesis of the A-E ring segment of ciguatoxin CTX3C was achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis.
Keywords:Polycyclic ethers  Ciguatoxin  Intramolecular allylation  Ring-closing metathesis
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