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Copper-free Sonogashira reactions of 4-hydroxycoumarins with alkynes |
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| Authors: | Yong Luo |
| Affiliation: | a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China |
| Abstract: | The palladium-catalyzed direct coupling reactions of 4-hydroxycoumarins with various alkynes under copper-free conditions are described. This transformation is highly effective under mild conditions and the desired products are obtained in good yields. |
| Keywords: | Alkyne Copper-free conditions 4-Hydroxycoumarin Palladium catalyst |
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