Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation |
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| Authors: | Simon J. Pridmore |
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| Affiliation: | Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK |
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| Abstract: | Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)3(CO)H2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. |
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| Keywords: | Ruthenium Catalysis Isomerisation Furans Pyrroles |
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