Silicon-based thiourea-mediated and microwave-assisted thio-Michael addition under solvent-free reaction conditions |
| |
| Authors: | Kamalakannan Prabakaran Machindra Gund Tae Kyu Kim Euh Duck Jeong Chae Young Oh Fazlur-Rahman Nawaz Khan Jong Sung Jin |
| |
| Affiliation: | (1) School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing, 210094, P.R. China;(2) Department of Science & Technology, Yancheng Teachers College, Yancheng, 224002, P.R. China; |
| |
| Abstract: | Silicon-based thiourea (SiliaBond® Thiourea) (Si-THU), a heterogeneous catalyst, has been applied to the highly selective C-S bond formation via Michael addition of thiols to α,β-unsaturated carbonyl compounds under solvent-free conditions at 55–60°C. The thio-Michael addition products were obtained in an excellent yield under optimised conditions. This methodology involving a metal-free as well as a metal scavenger catalyst has been found to be an alternative method for the thio-Michael addition reaction. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
