Cytotoxic metabolites from the wood-decayed fungus Xylaria sp. BCC 9653 |
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| Authors: | Pongcharoen Wipapan Rukachaisirikul Vatcharin Isaka Masahiko Sriklung Kanlayanee |
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| Affiliation: | Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla, Thailand. |
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| Abstract: | Chemical investigation of the wood-decayed fungus Xylaria sp. BCC 9653 has led to the isolation of a new methyl aminobenzoate (1) together with eleven known compounds. The structures were established by analysis of spectroscopic data. Cytochalasin D (2), one of the known metabolites, exhibited potent cytotoxicity against African green monkey kidney fibroblast (Vero) cells with an IC(50) value of 0.19 microM. |
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