The preparation of ribose-free ‘artificial dinucleotides’: A new approach to molecular recognition? |
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| Authors: | Jonathan L. Sessler Darren Magda Jeff Hugdahl |
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| Affiliation: | (1) Department of Chemistry, University of Texas, 78712 Austin, Texas, USA |
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| Abstract: | The synthesis of the cytosine-guanine linked dimer1, and its symmetric guanine-guanine analogue2 are described. Compound1 is the first homogeneous ribose-free system to be prepared and characterized in which molecular recognition by complementary guanine-cytosine base-pairing might be possible. It is thus prototypical of a new and potentially large class of  artificial oligonucleotides . |
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| Keywords: | Artificial dinucleotide molecular recognition cytosine-guanine dimer |
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