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Asteropterin, an inhibitor of cathepsin B, from the marine sponge Asteropus simplex
Authors:Shuhei Murayama  Shigeki Matsunaga
Affiliation:Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
Abstract:A new pteridine derivative, asteropterin (1), was isolated as a cathepsin B inhibitor from the marine sponge Asteropus simplex. The structure of asteropterin (1) was elucidated by the analysis of spectral data.
Keywords:Sponge   Inhibitor   Lumazine   Cathepsin B
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