Isostreptazolin and sannaphenol, two new metabolites from Streptomyces sannanensis |
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| Authors: | Zheng Dan Han Li Li Yiqing Li Jun Rong He Leng Qiao Jiang Yi Zhao Lixing Huang Xueshi |
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| Institution: | Ministry of Health Key Laboratory of Congenital Malformation, Laboratory of Metabolic Disease Research and Drug Development, China Medical University, Shenyang, China. |
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| Abstract: | Two new compounds, isostreptazolin (1) and sannaphenol (2), were isolated from the culture broth of Streptomyces sannanensis and their structures elucidated on the basis of 1D and 2D NMR as well as MS, IR and UV spectroscopic data analysis. The cytotoxic activity of 1 and 2 were evaluated. Both compounds were inactive against H460 and HeLa cell lines at 100 mM. |
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