A microfluidic-based nanoscope |
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Authors: | S W Stone C D Meinhart S T Wereley |
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Institution: | (1) Department of Mechanical and Environmental Engineering University of California, Santa Barbara, CA 93106, USA E-mail: stones@engineering.ucsb.edu, US;(2) Department of Mechanical Engineering, 1288 Mechanical Engineering Building, Purdue University West Lafayette, IN 47907, USA, US |
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Abstract: | A novel technique for noninvasively measuring the shapes of walls with resolution approaching tens of nanometers is presented.
The nanoscope measures local wall position by measuring the velocity of a fluid with micron-scale spatial resolution as it
flows over a surface. The location of the wall is estimated by assuming the no-slip velocity condition at the wall and extrapolating
the velocity profile to zero. Nanoscope measurements were obtained in a 30 × 300-μm channel. The wall shape of the glass microchannel
was determined to be flat to within a root mean square uncertainty of 62 nm. Numerical simulations show that noise in the
velocity measurements contributes significantly to uncertainty in wall position. The technique can be used to measure surfaces
that are immersed in liquids and in geometries that do not provide exposed surfaces, where traditional nanoscope techniques
such as scanning probe microscopes (SPM) are not applicable.
Received: 2 March 2001 / Accepted: 19 October 2001 |
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