Synthesis,Chemical Characterization,DNA Interaction and Antioxidant,Studies of New Nitrosubstituted Thioureas and Their Copper Complexes |
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| Authors: | Jahangeer Patujo Amin Badshah Raja Azadar Hussain Muhammad Nawaz Tahir Shaista Tahir Muhammad Khawar Rauf |
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| Abstract: | In the present work new nitro substituted thioureas, and their copper complexes have been synthesized and characterized by FTIR and multinuclear NMR techniques. Some of the compounds namely 1‐benzoyl‐3‐(4‐chloro‐3‐nitrophenyl) thiourea (A‐1), 1‐benzoyl‐3‐(4‐chloro‐3‐nitrophenyl) thiourea (A‐2) and 1‐benzoyl‐3‐(2‐methoxy‐4‐nitrophenyl) thiourea (A‐2) have also been characterized by single crystal XRD. All the synthesized compounds have been screened for DNA binding potencies (using cyclic voltametry, UV‐vis spectroscopy) and free radical scavanging activities. |
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| Keywords: | Thiourea copper complexes Cyclic voltammetry DNA binding studies |
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