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Tandem Synthesis of Bicyclic ortho‐Aminocarbonitrile Derivatives in Ionic Liquids |
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| Authors: | Y. Wan X‐X. Zhang L‐L. Zhao C. Wang L‐F. Chen G‐X. Liu S‐Y. Huang S‐N. Yue W‐L. Zhang H. Wu |
| Abstract: | An efficient synthesis of 2‐amino‐4a,5,6,7‐tetrahydronaphthalene‐1,3,3(4H)‐tricarbonitriles via the tandem four‐component condensation of one equivalent of aromatic aldehyde, cyclohexanone, and two equivalents of malononitrile in ionic liquids was undertaken. Up to four new bonds and one new ring were formed in one‐pot with water as the only by‐product in this multi‐component procedure. |
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