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Phenolic Metabolites from the Stems and Leaves of Sophora flavescens
Authors:Chi Zhang  Yan‐Min Wang  Feng‐Chun Zhao  Liang‐Mian Chen  Qi‐Wei Zhang  Hui‐Min Gao  Zhi‐Min Wang
Institution:1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, P.?R. China (phone/fax: +86‐10‐84014128);2. National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, P.?R. China;3. Tianjin University of Traditional Chinese Medicine, Tianjin 300193, P.?R. China
Abstract:Two new compounds, (?)‐(6aR,11aR)‐4‐methoxy‐8,9‐(methylenedioxy)pterocarpan 3‐Oβ‐D ‐glucopyranoside ( 1 ) and 5‐hydroxy‐7‐methoxyisoflavone 4′‐Oβ‐D ‐xylopyranosyl‐(1→6)‐β‐D ‐glucopyranoside ( 2 ), were isolated, together with 30 known compounds from the stems and leaves of Sophora flavescens Aition . Their structures were elucidated by extensive spectroscopic analysis, including HR‐ESI‐MS data. A preliminary comparison of phenolic metabolite profiles, based on the qualitative HPLC analysis, indicated that the composition of the roots and the aerial parts were significantly different.
Keywords:Sophora flavescens  Isoflavones  Lignans  Pterocarpans
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