Sesquiterpenoids and Their Glycosides from Gynura procumbens |
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| Authors: | Ying Zhang Kun Jiang Yi‐Ming Zhai Jun‐Jie Tan Da‐Li Meng Sha‐Li Guo Shi‐Jin Qu Chang‐Heng Tan |
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| Affiliation: | 1. Department of Natural Medicinal Chemistry, Shanghai Institute of Materia Medica, CAS, 555 Zuchongzhi Road, Shanghai 201203, P.?R. China (phone/fax: +86‐21‐50806728);2. Key Laboratory of Structure‐Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China (phone: +86‐24‐23986475) |
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| Abstract: | Chemical investigation of the MeOH extract of the leaves of Gynura procumbens (Lour .) Merr . afforded one new sesquiterpenoid, muurol‐4‐ene‐1β,3β,10β‐triol ( 1 ), and two sesquiterpene glycosides, muurol‐4‐ene‐1β,3β,10β‐triol 3‐O‐β‐D ‐glucopyranoside ( 2 ) and muurol‐4‐ene‐1β,3β,15‐triol 3‐O‐β‐D ‐glucopyranoside ( 3 ), together with three known sesquiterpenoids. Their structures were elucidated on the basis of spectroscopic analyses and chemical methods. |
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| Keywords: | Gynura procumbens Muurol‐4‐ene‐1β ,3β ,10β ‐triol Sesquiterpenoids Glycosides |
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