New Antiproliferative Tricyclic Sesquiterpenoid from the Leaves of Ocimum sanctum |
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| Authors: | Deepika Singh Prabir Kumar?Chaudhuri Mahendra P Darokar |
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| Institution: | 1. Medicinal Chemistry Division, CSIR‐Central Institute of Medicinal and Aromatic Plants, PO CIMAP, Lucknow 226015, India, (phone: +91‐522‐2718593;2. fax: +91‐522‐2357136);3. Molecular Bioprospection Department, CIMAP, Lucknow, India |
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| Abstract: | A new tricyclic sesquiterpenoid 2‐(hydroxymethyl)‐5,5,9‐trimethyltricyclo7.2.0.03,6]undecan‐2‐ol ( 1 ), was identified from the leaves of Ocimum sanctum, and its structure was elucidated by extensive NMR and ESI‐MS analyses. Compound 1 was found to have potent antiproliferative activity against the MCF‐7 cell line. |
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| Keywords: | Ocimum sanctum Sesquiterpenoids Antiproliferative activity |
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