| 当归水提物化学成分的研究 |
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| 引用本文： | 张丽筑,韩应莲,郝小燕.当归水提物化学成分的研究[J].贵州科学,2006,24(3):28-30. |
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| 作者姓名： | 张丽筑 韩应莲 郝小燕 |
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| 作者单位： | 贵阳医学院,药学院,贵州,贵阳,550004;贵阳医学院,药学院,贵州,贵阳,550004;贵阳医学院,药学院,贵州,贵阳,550004 |
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| 基金项目： | 贵州省中药现代化专项基金 |
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| 摘 要： | 目的:研究当归 (Angelica sinensis(Oliv) Diels)的化学成分.方法:采用大孔树脂和硅胶柱层析进行分离纯化,通过理化和波谱分析鉴定其化学结构.结果:从当归水提物的大孔树脂20～40%乙醇洗脱部分分离得到3个化合物,经理化和波谱分析鉴定为6,7-二羟基藁本内酯1 (Z-6,7-cis-dihydroxyligustilide)、邻苯二甲酸二(2-乙基)己酯2 (bis(2-ethylhexyl)phthalate)和布雷菲德菌素A 3 (brefeldin A).结论:化合物3为青霉菌属典型的代谢产物,有可能是当归根际真菌的代谢产物.
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| 关 键 词： | 当归 6 7-二羟基藁本内酯 邻苯二甲酸二(2-乙基)己酯 布雷菲德菌素A |
| 文章编号： | 1003-6563（2006）03-0028-03 |
| 收稿时间： | 2005-10-16 |
| 修稿时间： | 2005年10月16 |
STUDIES ON CHEMICAL CONSTITUENTS FROM ANGELICA SINENSIS(OLIV) DIELS |
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| ZHANG Li-zhu,HAN Ying-lian,HAO Xiao-yan.STUDIES ON CHEMICAL CONSTITUENTS FROM ANGELICA SINENSIS(OLIV) DIELS[J].Guizhou Science,2006,24(3):28-30. |
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| Authors: | ZHANG Li-zhu HAN Ying-lian HAO Xiao-yan |
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| Institution: | School of Pharmacy, Guiyang Medical College, Guiyang 550004 |
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| Abstract: | Objective: Studies on chemical constituents from Angelica sinensis(Oliv) Diels.Method: Isolation and purification was carried out by chromatography on macroporous resin and silica gel,and the chemical constituents were identified by physico-chemical properties and spectral analysis.Result: three compounds were isolated from 20~40% enthanol fractions of column chromatography over macroporous resin,and their structure were elucidated as Z-6,7-cis-dihydroxyligustilide 1,bis(2-ethylhexyl)phthalate 2 and brefeldin A 3 based on physico-chemical properties and spectral analysis.Conclusion: compound 3 was the typical metabolite produced by Penicillium sp.and may be a metabolite from the rhizosphere microorganisms of Angelica sinensis(Oliv) Diels. |
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| Keywords: | Angelica sinensis(Oliv) Diels Z-6 7-cis-dihydroxyligustilide bis(2-ethylhexyl)phthalate brefeldin A |
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