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An efficient synthesis of N-Boc-(2S,3S)-3-hydroxy-2-phenyl piperidine and N-Boc-safingol |
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| Authors: | Maddimsetti Venkateswara RaoKotha kapu Sridhar Reddy Batchu Venkateswara Rao |
| Institution: | Organic and Biomolecular Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500607, India |
| Abstract: | An efficient strategy has been developed for the stereo selective synthesis of N-Boc-(2S,3S)-3-hydroxy-2-phenyl piperidine and N-Boc-safingol from benzaldehyde and N-Boc-imine. |
| Keywords: | N-Boc-imine Manich reaction Wittig reaction DIBALH-reduction Cyclisation Ru-oxidation BH3-reduction |
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