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| Theoretical Study on the Mechanism Properties of a Novel Trans-platinum Antitumor Drug | |
| 基金项目： | This work was supported by the Science Foundation of Jinan University (639) |
| 摘 要： | 1 INTRODUCTION Cis-diamminedichloroplatinum(II) (cis-DDP) is a widely used drug in dealing with many human carcinomas, such as testicular carcinoma, ovarian carcinoma, etc.1～4]. Despite of its great success in treating many kinds of cancers, the antitumor drug does have many limitations, for example, several side effects or both intrinsic and acquired resis- tance5, 6]. In order to solve these problems, various platinum complexes have been tested over the past years7～19]. The clas… |
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