Highly Active Multidentate Ligand‐Based Alkyne Metathesis Catalysts |
| |
Authors: | Dr Ya Du Dr Haishen Yang Chengpu Zhu Michael Ortiz Kenji D Okochi Prof?Dr Richard Shoemaker Dr Yinghua Jin Prof?Dr Wei Zhang |
| |
Institution: | Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO, USA |
| |
Abstract: | Alkyne metathesis catalysts composed of molybdenum(VI) propylidyne and multidentate tris(2‐hydroxylbenzyl)methane ligands have been developed, which exhibit excellent stability (remains active in solution for months at room temperature), high activity, and broad functional‐group tolerance. The homodimerization and cyclooligomerization of monopropynyl or dipropynyl substrates, including challenging heterocycle substrates (e.g., pyridine), proceed efficiently at 40–55 °C in a closed system. The ligand structure and catalytic activity relationship has been investigated, which shows that the ortho groups of the multidentate phenol ligands are critical to the stability and activity of such a catalyst system. |
| |
Keywords: | alkylidyne alkyne metathesis homogeneous catalysis molybdenum multidentate ligand |
|
|