Synthesis of Highly Functionalized Isoxazolinediones from One-pot Reaction of Alkylidene <Emphasis Type="Italic">Meldrum</Emphasis>’s Acid with Alkyl Isocyanides in the Presence of Arylhydroxylamines |
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| Authors: | Azizollah Habibi Leyla Mousavifar Issa Yavari Mohammad R Yazdanbakhsh |
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| Institution: | (1) Faculty of Chemistry, Tarbiat Moallem University, Tehran, Iran;(2) Chemistry Department, Tarbiat Modarres University, Tehran, Iran;(3) Chemistry Department, Guilan University, Rasht, Guilan, Iran |
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| Abstract: | Summary. Alkyl isocyanides undergo a smooth reaction with alkylidene Meldrum’s acids in the presence of arylhydroxylamines to produce N
1-alkyl-2-(3,5-dioxo-2-aryltetrahydro-4-isoxazolyl)alkanamides in high yields. |
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| Keywords: | , Isoxazolinedione, Arylhydroxylamine, Alkyl isocyanide, Alkylidene Meldrum’,s acid, |
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