Facile and efficient synthesis of a new class of bis(3′-indolyl)pyridine derivatives via one-pot multicomponent reactions |
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| Authors: | Song-Lei Zhu Shun-Jun Ji Xiao-Ming Su Yu Liu |
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| Institution: | a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou(Soochow) University, Suzhou 215123, People’s Republic of China
b Department of Chemistry, Xuzhou Medical College, Xuzhou 221002, People’s Republic of China |
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| Abstract: | A series of 4-aryl-3,5-dicyano-2,6-di(3′-indolyl)pyridine derivatives were synthesized via a one-pot multicomponent reaction of aromatic aldehydes, 3-cyanoacetyl indoles, and ammonium acetate under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time, and straightforward procedure. |
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| Keywords: | Bisindole 3 5-Dicyanopyridine Multicomponent reactions Microwave irradiation |
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