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Copper(I)-doped Wyoming’s montmorillonite for the synthesis of disubstituted 1,2,3-triazoles
Authors:Ibtissem Jlalia  Hichem Elamari  Faouzi Meganem  Christian Girard
Institution:a Laboratoire de Pharmacologie Chimique et Génétique UMR8151 CNRS—U640 INSERM—IFR2769, Ecole Nationale Supérieure de Chimie de Paris, 11, rue Pierre et Marie Curie, 75005 Paris, France
b Laboratoire de Synthèse Organique et Application, Faculté des Sciences de Bizerte, Université du 7 Novembre à Carthage, 7021 Jarzouna Bizerte, Tunisia
Abstract:A new catalytic system based on copper(I)-doped Wyoming’s montmorillonite was elaborated. This system was studied and was found to catalyze the formation of 1,4-disubstituted 1,2,3-triazoles when starting from azides and alkynes. It was used for the synthesis of a few triazole derivatives to show its usefulness.
Keywords:Click-chemistry  Huisgen  Triazole  Copper catalysis  Wyoming montmorillonite
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