Synthetic studies on dragmacidin D: synthesis of the left-hand fragment |
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Authors: | Minoru Ikoma Makoto Sasaki |
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Institution: | Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan |
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Abstract: | We report a synthesis of a left-hand fragment of bis(indole)-class marine alkaloid, dragmacidin D. The synthesis features Suzuki-Miyaura reaction for the coupling of imidazolyl boronic acid and (4-indolyl)vinyl bromide. |
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