Highly chemoselective reductive amination-coupling by one-pot reaction of aldehydes, HMDS and NaBH4 |
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| Authors: | Najmedin Azizi Alireza Khejeh Amiri |
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| Institution: | a Department of Chemistry, Sharif University of Technology, PO Box 11465-9516, Tehran 11365, Iran
b Chemistry and Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran |
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| Abstract: | An efficient and highly chemoselective synthesis of symmetrical secondary amines via reductive amination of aldehydes with inexpensive and commercially available HMDS and sodium borohydride in high to quantitative yields is reported. |
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