Synthesis of porphyrin-quinolone conjugates |
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| Authors: | Fernanda da C Santos Anna C Cunha Augusto C Tomé Vitor F Ferreira |
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| Institution: | a University of Aveiro, Department of Chemistry, 3810-193 Aveiro, Portugal
b Universidade Federal Fluminense, Departamento de Química Orgânica, 24020-141 Niterói, Rio de Janeiro, Brazil |
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| Abstract: | meso-Tetrakis(pentafluorophenyl)porphyrin reacts with propargyl alcohol to afford porphyrins substituted with one, two, three or four prop-2-yn-1-yloxy groups in the 4-position of the meso-aryl groups. These new porphyrin derivatives react with a 6-azidoquinolone under ‘click-chemistry’ conditions to give porphyrin-quinolone conjugates linked by 1,2,3-triazole units. |
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| Keywords: | Porphyrins Triazoles Quinolones Click-chemistry |
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