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Bischler-Napieralski cyclocondensation in the synthesis of new 11H-pyrimido[4,5-b][1,4]benzodiazepines |
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| Authors: | Justo Cobo Manuel Nogueras Ricaurte Rodríguez |
| Institution: | a Departamento de Química Inorgánica y Orgánica, Universidad de Jaén, 23071 Jaén, Spain b Department of Chemistry, University of Aberdeen, Old Aberdeen, AB24 3UE Scotland, UK c Departamento de Química, Universidad Nacional de Colombia, Bogotá AA 14490, Colombia |
| Abstract: | A synthetic strategy based on nitrosation-aminolysis-nitroso reduction and Bischler-Napieralski cyclocondensation has been developed for the synthesis of a family of 2-amino-4-methoxy-11H-pyrimido4,5-b]1,4]benzodiazepines. |
| Keywords: | Bischler-Napieralski cyclocondensation Pyrimidobenzodiazepines Nitrosation 2-Aminopyrimidines Aminolysis |
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