Suffruticosine, a novel octacyclic alkaloid with an unprecedented skeleton from Securinegasuffruticosa (Pall.) Rehd. |
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Authors: | Song Qin Yu-Cheng Gu |
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Institution: | a State Key Laboratory of Drug Research, Shanghai Institute of Material Medica, Chinese Academy of Sciences, Shanghai 201203, China b School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China c Syngenta, Jealott’s Hill International Research Centre, Bracknel, Berkshire RG42 6EY, UK |
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Abstract: | A novel securinega alkaloid, suffruticosine (1), was isolated from the leaves and barks of Securinegasuffruticosa. The structure of 1, characterized by a fused complex octacyclic system, was elucidated by combined spectroscopic techniques, especially 2D NMR and CD spectral analyses. |
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Keywords: | Securinegasuffruticosa Securinega alkaloids Suffruticosine |
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