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Bromohydrin reactions of Grieco’s bicyclic lactone
Authors:Rodolfo Tello-Aburto  Dale C. Swenson
Affiliation:a Medicinal and Natural Products Chemistry, The University of Iowa, Iowa City, IA 52242, United States
b Department of Chemistry, X-ray Diffraction Laboratory, The University of Iowa, Iowa City, IA 52242, United States
Abstract:The bromohydrin reaction in Grieco’s bicyclic lactone 1 was reinvestigated. Two regioisomeric bromohydrins were obtained (2 and 8), and their configurations were unambiguously determined by X-ray diffraction analyses.
Keywords:Grieco&rsquo  s lactone   Bromohydrin
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