A mild Boc deprotection and the importance of a free carboxylate |
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| Authors: | Ali Thaqi Janet L. Scott |
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| Affiliation: | a Centre for Green Chemistry, Monash University, Wellington Road, Clayton, Victoria 3800, Australia
b Chemistry, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia |
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| Abstract: | We report a facile and rapid removal of Boc protecting groups using microwave heating in H2O, with deprotection only requiring a free carboxylic acid group in the starting material. Unlike previous approaches, no additional reagents are required. |
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