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A simple and efficient one-pot synthesis of 1,4-dihydropyridines using heterogeneous catalyst under solvent-free conditions
Authors:Muchchintala Maheswara  Vidavalur Siddaiah  Yerra Koteswara Rao  Yew-Min Tzeng  Chenchugari Sridhar  
Institution:

aSri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati 517502, India

bInstitute of Biotechnology, Chaoyang University of Technology, Wufeng 41349, Taiwan, ROC

Abstract:One-pot condensation of β-dicarbonyl compounds with aldehydes and ammonium acetate in the presence of HClO4–SiO2 at 80 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable, reusable and efficiently used under reaction conditions.
Keywords:β-Dicarbonyl compounds  1  4-Dihydropyridines  HClO4–SiO2  Recyclable heterogeneous catalyst  Solvent-free conditions
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