Fe3O4 nanoparticles: As an efficient,green and magnetically reusable catalyst for the one-pot synthesis of 1,8-dioxo-decahydroacridine derivatives under solvent-free conditions |
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Authors: | Mohammad Ali Ghasemzadeh Javad Safaei-Ghomi Halimeh Molaei |
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Institution: | Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167 Kashan, I.R. Iran |
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Abstract: | An efficient and environmentally friendly method for the one-pot synthesis of 1,8-dioxo-decahydroacridines has been developed in the presence of Fe3O4 nanoparticles. The multicomponent reactions of aldehydes, dimedone and amines were carried out under solvent-free conditions to obtain some 1,8-dioxo-9-aryl-10-aryl-decahydroacridine derivatives. The present approach provides several advantages including high yields, short reaction times, little catalyst loading and facile catalyst separation. |
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