A facile one-pot highly chemo- and regioselective synthesis of the novel heterocyclic system indolo[1,2-c]azolo[1,5-a]quinazoline-8,10-dione |
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| Authors: | Olesya N Petrova Lali L Zamigajlo Svetlana V Shishkina Oleg V Shishkin Vladimir I Musatov Alexander V Borisov Victoria V Lipson |
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| Institution: | 1. SSI “Institute for Single Crystals” of NASU, Lenin Ave. 60, Kharkov 61001, Ukraine;2. V.N. Karazin Kharkov National University, Organic Chemistry Department, Svobody Sq. 4, Kharkov 61077, Ukraine;3. Institute of Organic Chemistry of NASU, Murmanska St. 5, Kyiv 02660, Ukraine;4. Antidiabetic Drug Laboratory, SI “V.Ya. Danilevsky Institute for Endocrine Pathology Problems”, Artema St. 10, Kharkov 61002, Ukraine |
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| Abstract: | A series of novel indolo1,2-c]azolo1,5-a]quinazoline-8,10-diones was obtained by a multi-component reaction between cyclic 1,3-diketones, α-aminoazoles, and glyoxal. The unexpected cyclization process was established by NMR spectroscopy and X-ray diffraction measurements. |
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| Keywords: | Cyclic 1 3-diketones α-Aminoazoles Glyoxal Multicomponent reaction |
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