多接收器电感耦合等离子体质谱方法的开发和应用进展

稳定同位素分析是分析化学一项颇具前景的分支,通过精确测定物质的稳定同位素比值,可以追溯物质来源并探究其转化过程。高精度稳定同位素分析技术的进步依赖于新一代质谱仪的不断发展。其中,多接收器电感耦合等离子体质谱(MC-ICP-MS)是近年发展迅速的一种同位素组成测定工具。稳定同位素分析对样品基质十分敏感,复杂基质能严重干扰同位素测定的精密度和准确度。这对MC-ICP-MS的样品净化提出了极高要求,目前也是同位素分析领域的热点问题。该文聚焦于近年来MC-ICP-MS在样品净化及仪器联用方法方面的相关研究进展,并展望了MC-ICP-MS稳定同位素分析的应用前景。

Recent advances in method development and application of multi-collector inductively coupled plasma mass spectrometry

Stable isotopic analysis is an important branch of analytical chemistry.Accurate determination of the stable isotopic compositions of substances is critical for tracing their sources and investigating their transformation processes.The new generation of mass spectrometry technology has greatly facilitated the development of high-precision stable isotopic analysis methods.In particular,multi-collector inductively coupled plasma mass spectrometry(MC-ICP-MS)has emerged as a powerful tool for isotopic composition determination.However,isotopic analysis by MC-ICP-MS is highly sensitive to the sample matrix,which may compromise the precision and accuracy of the analysis.Therefore,it is particularly important to reduce the sample matrix effect using efficient sample purification techniques.This article summarizes the recent progress in sample purification and instrument hyphenation methods for MC-ICP-MS,and provides perspectives on the future application of MC-ICP-MS in different fields.