Pd/C‐Catalyzed Carbonylative Esterification of Aryl Halides with Alcohols by Using Oxiranes as CO Sources |
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| Authors: | Byul‐Hana Min Dr Dong‐Su Kim Hyo‐Soon Park Prof?Dr Chul‐Ho Jun |
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| Institution: | Department of Chemistry, Yonsei University, Seoul, Republic of Korea |
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| Abstract: | A carbonylative esterification reaction between aryl bromides and alcohols, promoted by Pd/C and NaF in the presence of oxiranes, has been developed. In this process, oxiranes serve as sources of carbon monoxide by their conversion to aldehydes through a palladium‐promoted Meinwald rearrangement pathway. Intramolecular versions of this process serve as methods for the synthesis of lactones and phthalimides. |
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| Keywords: | carbonylation cross-coupling cyclization lactones palladium |
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