Palladium‐Catalyzed Arylation of Arylboronic Acids with Yagupolskii–Umemoto Reagents

A Pd‐catalyzed Suzuki cross‐coupling of arylboronic acids with Yagupolskii–Umemoto reagents was explored. In contrary to trifluoromethylations, the Pd‐catalyzed reaction of R?B(OH)₂ and Ar₂SCF₃]⁺OTf]^? provided the arylation products (R?Ar) in good to high yields. The reaction confirms that the S?Ar bonds of Ar₂SCF₃]⁺OTf]^? can be readily cleaved in the presence of Pd complexes. The relatively electron‐poor aryl groups of asymmetric Ar¹Ar²SCF₃]⁺OTf]^? salts are more favorably transferred compared to the electron‐rich ones. This reaction represents the first report of utilization of Ar₂SCF₃]⁺OTf]^? as arylation reagents in organic synthesis.