Covalent sidewall functionalization of single-walled carbon nanotubes by amino acids |
| |
Authors: | M X Pulikkathara V N Khabashesku |
| |
Institution: | (1) Department of Chemistry, Rice Quantum Institute and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, Houston, Texas 77005-1982, USA |
| |
Abstract: | Single-walled carbon nanotubes (SWNTs) with amino acids covalently attached to their side walls, viz., “nanotube-aminoacids,” have been prepared starting from colloidal solutions of fluorinated SWNTs (F-SWNTs) and amino acids
in o-dichlorobenzene and heating at 80–150 °C in the presence of pyridine. The syntheses were carried out with the F-SWNTs of
approximately 2: 1 (C: F) stoichiometry and several natural α-aino acids with both pro-tected and unprotected carboxyl groups,
such as glycine ethyl ester hydrochloride, L-serine ethyl ester hydrochloride, l-cysteine, and trans-4-hydroxy-l-proline. The nanotube-aminoacids have been characterized by Raman and FTIR spectroscopy, atomic force, scanning, and transmission
electron microscopies, and thermal gravimetric analysis (TGA). Based on TGA data, the degree of sidewall functionalization
in the synthesized SWNT derivatives was estimated to be in the range from one of 32 to one of 8 carbon atoms, depending on
the amino acid nature and reaction conditions used. The amino acid-functionalized SWNTs, prepared in this work by simple and
inexpensive one-step method, can be valuable precursors for peptide synthesis and targeted drug delivery, design and fabrication
of nanocomposites and fibers, and other biomedical and engineering applications.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1035–1043, May, 2008. |
| |
Keywords: | carbon nanotubes functionalization amino acids solubility |
本文献已被 SpringerLink 等数据库收录! |
|