Immunoassays in microfluidic systems |
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| Authors: | Alphonsus H C Ng Uvaraj Uddayasankar Aaron R Wheeler |
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| Institution: | (1) Institute for Biomaterials and Biomedical Engineering, University of Toronto, 164 College St., Toronto, ON, M5S 3G9, Canada;(2) The Terrence Donnelly Centre for Cellular and Biomolecular Research, 160 College St., Toronto, ON, M5S 3E1, Canada;(3) Department of Chemistry, University of Toronto, 80 St George St., Toronto, ON, M5S 3H6, Canada; |
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| Abstract: | Immunoassays have greatly benefited from miniaturization in microfluidic systems. This review, which summarizes developments
in microfluidics-based immunoassays since 2000, includes four sections, focusing on the configurations of immunoassays that
have been implemented in microfluidics, the main fluid handling modalities that have been used for microfluidic immunoassays,
multiplexed immunoassays in microfluidic platforms, and the emergence of label-free detection techniques. The field of microfluidic
immunoassays is continuously improving and has great promise for the future. |
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