An approach to detection capabilities estimation of analytical procedures based on measurement uncertainty |
| |
Authors: | Juan Jiménez-Chacón Manuel Alvarez-Prieto |
| |
Institution: | (1) Institute of Science and Technology of Materials, University of Havana, Zapata y G, s/n, Havana, Cuba; |
| |
Abstract: | Detection capabilities are important performance characteristics of analytical procedures. There are several conceptual approaches
on the subject, but in most of them a level of ambiguity is presented. It is not clear which conditions of measurements should
be used, and there is a relative lack of definition concerning blanks. Moreover, there are no systematic experimental studies
concerning the influence of uncertainty associated with bias evaluation. A new approach based on measurement uncertainty is
presented for estimating quantities that characterize capabilities of detection. It can be applied to different conditions
of measurement and it is not necessary to perform an additional experiment with blanks. Starting from a modelling process
of the combined uncertainty of concentration, it is possible to include in the estimated quantities the effects due to random
errors and the uncertainty associated to evaluation of bias. The detection capabilities are then compared with the results
obtained using some other relevant approaches. Slightly higher values were obtained with the measurement uncertainty approach
due to inclusion of uncertainty associated with bias. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|