A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols |
| |
| Authors: | Baxendale Ian R Ley Steven V Smith Christopher D Tranmer Geoffrey K |
| |
| Institution: | Innovative Technology Centre, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW. |
| |
| Abstract: | A general flow process for the multi-step assembly of peptides has been developed and this procedure has been used to successfully construct a series of Boc, Cbz and Fmoc N-protected dipeptides in excellent yields and purities, including an extension of the method to enable the preparation of a tripeptide derivative. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
