FLUORESCENCE BEHAVIOUR OF SEQUENTIAL TYROSYL POLYPEPTIDES |
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| Authors: | Arun V Pantar M V R Rao M Atreyi Satish Kumar |
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| Institution: | Department of Chemistry, University of Delhi, Delhi-110007, India;Department of Biophysics, Indian Veterinary Research Institute, Izatnagar (U.P.), India |
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| Abstract: | Abstract— Fluorescence behaviour of three sequential tyrosyl copolypeptides, (Gly-Tyr)35, (Ala-Tyr)29 and (Val-Tyr)22, was studied in alkaline solutions, in which ionisation of tyrosyl hydroxyl was 80%. Irradiation at 280 nm in all the three systems lead to the formation of a photoproduct which fluoresced intensely at 410 nm. The facility of the photoreaction depended markedly on the nature of the comonomer of tyrosine and the conformation of the polypeptide chain. As a result of photoproduct formation, the polypeptide backbone is hindered in acquiring more ordered structure at a lower degree of tyrosyl ionisation. |
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