Bismuth triflate-catalyzed three-component mannich-type reaction |
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Authors: | Ollevier Thierry Nadeau Etienne |
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Institution: | Département de chimie, Université Laval, Québec, Canada G1K 7P4. thierry.ollevier@chm.ulaval.ca |
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Abstract: | Bismuth triflate catalyzes the Mannich-type reaction of a variety of in situ generated aldimines using aldehydes, anilines, and silyl enol ethers in a three-component reaction. The reaction proceeds rapidly and affords the corresponding protected beta-amino ketones in high yields (up to 94%). |
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