A facile synthesis of phytosphingosine from diisopropylidene-D-mannofuranose |
| |
Authors: | Chiu Hsin-Yi Tzou Der-Lii M Patkar Laxmikant Narhari Lin Chun-Cheng |
| |
Institution: | Institute of Chemistry, Academia Sinica, Nankang, Taipei 115, Taiwan. |
| |
Abstract: | In the present study, an efficient method with a high overall yield for preparing phytosphingosine and an analogue was developed. Starting with commercially available 2,3;5,6-di-O-isopropylidene-d-mannofuranose, a variety of lipid moieties were incorporated to obtain phytosphingosine and an analogue. Through an eight-step manipulation, phytosphingosine was obtained with an overall yield of 57%. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|