| Three-component synthesis of imidazo[1,2-c]pyrimidines using silica sulfuric acid(SSA)简 |
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| 作者姓名： | Mohammad Bakherad Ali Keivanloo Masoumeh Siavashi Mina Omidian |
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| 作者单位： | School of Chemistry, Shahrood University of Technology, Shahrood 361999S161, lran |
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| 基金项目： | We are grateful to the Research Council of Shahrood University of Technology for the financial support of this work. |
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| 摘 要： | This letter describes a simple and efficient synthesis of 3-（cyclohexylamino）-7-hydroxy-2-arylimi- dazo1,2-c]pyrimidin-5（6H）-one via a one-pot three-component reaction of cyclohexyl isocyanide, an aldehyde, and 4-amiopyrimidine-2,6-diol in the presence of a catalytic amount of SSA.
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| 关 键 词： | SSA 合成 咪唑 嘧啶 三分量 硫酸 硅胶 环己基 |
| 收稿时间： | 2013-07-01 |
| 修稿时间： | 2013-09-10 |
Three-component synthesis of imidazo[1,2-c]pyrimidines using silica sulfuric acid (SSA) |
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| Mohammad Bakherad,Ali Keivanloo,Masoumeh Siavashi,Mina Omidian.Three-component synthesis of imidazo[1,2-c]pyrimidines using silica sulfuric acid (SSA)[J].Chinese Chemical Letters,2014,25(1):149-151. |
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| Authors: | Mohammad Bakherad Ali Keivanloo Masoumeh Siavashi Mina Omidian |
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| Institution: | School of Chemistry, Shahrood University of Technology, Shahrood 3619995161, Iran |
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| Abstract: | This letter describes a simple and efficient synthesis of 3-(cyclohexylamino)-7-hydroxy-2-arylimidazo1,2-c]pyrimidin-5(6H)-one via a one-pot three-component reaction of cyclohexyl isocyanide, an aldehyde, and 4-amiopyrimidine-2,6-diol in the presence of a catalytic amount of SSA. |
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| Keywords: | Multi-component reaction (MCR) Silica sulfuric acid Isocyanide Imidazo[1 2-c] pyrimidines |
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