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A Facile Synthesis of 2‐Substituted 2,3‐Dihydro‐4(1H)‐Azuleno[2,1‐d]Pyrimidinones
Authors:Dao‐Lin Wang  Wei Li  Jiao Xu  Yuan‐Feng Li  Shao‐Fei Li  Li‐Nan Lin  Kimiaki Imafuku
Institution:1. College of Chemistry and Chemical Engineering, Liaoning Key Laboratory of Synthesis and Application of Functional Compound, Bohai University, Jinzhou, China;2. Cosmetology Department, Jiamusi Institute, Heilongjiang University of Chinese Medicine, Jiamusi, China;3. Department of Chemistry, Faculty of Science, Kumamoto University, Kumamoto, Japan
Abstract:A facile, efficient, and novel approach to access 2‐substituted 2,3‐dihydro‐4(1H)‐azuleno2,1‐d]pyrimidinones was developed by condensation of 2‐amino‐1‐carbamoyl‐3‐phenylazulene with ary1 aldehydes or ketones in ionic liquids by catalyzed p‐toluenesulfonic acid.
Keywords:
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