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Aminomethylation of 3-aryl-7-hydroxycoumarins
Authors:S P Bondarenko  M S Frasinyuk  V P Khilya
Institution:(1) Taras Shevchenko Kiev National University, Kiev, 01033, Ukraine;
Abstract:The reaction of the analogs of natural 3-arylbenzopyran-2-ones with electrophilic reagents of aminal structure was studied. Substituted 8-aminomethyl-3-aryl-7-hydroxycoumarins were synthesized. The optimum conditions were determined for the production of 9-alkyl- and 9-(het)arylmethyl derivatives of 3-aryl-9,10-dihydro-2H,8H-chromeno8,7-e]1,3]oxazin-2-one in the series of analogs of natural 3-arylbenzopyran-2-ones.
Keywords:
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