| 吡唑衍生物的合成及生物活性 |
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| 引用本文： | 李正名 陈寒松. 吡唑衍生物的合成及生物活性[J]. 高等学校化学学报, 1997, 18(11): 1794-1799 |
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| 作者姓名： | 李正名 陈寒松 |
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| 作者单位： | 南开大学元素有机化学研究所!天津，300071 |
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| 基金项目： | 国家自然科学基金!29232010 |
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| 摘 要： | 以５－吡唑甲酰肼（７，８）为原料合成了４类共３０种新化合物，这些化合物的结构均经＾１Ｈ ＮＭＲ，元素分析证实，部分化合物还经过了ＭＳ、ＩＲ确证，对大部分化合物做了生物活性测试，结果表明均具有一定的杀菌和除草活性。
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| 关 键 词： | 吡唑衍生物 生物活性 吡唑甲酰肼 |
Synthesis and Biological Activity of Pyrazole Derivatives |
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| LI Zheng-Ming, CHEN Han-Song, ZHAO Wei-GuangZHANG Kai, HUANG Xing-Sheng. Synthesis and Biological Activity of Pyrazole Derivatives[J]. Chemical Research In Chinese Universities, 1997, 18(11): 1794-1799 |
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| Authors: | LI Zheng-Ming CHEN Han-Song ZHAO Wei-GuangZHANG Kai HUANG Xing-Sheng |
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| Abstract: | Thirty new pyrazole acylhydrazine derivatives containing carboxylate,sulfonylate, hydrazone and dipyrazole ketone were synthesized from the intermediate 1, 3,4-substituted-5-pyrazole carboxylic hydrazide(7,8). Their structures were confirmed by 1H NMRand elemental analysis. The preliminary biological tests showed that several compounds havesome fungicidal and herbicidal activity. |
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| Keywords: | Pyrazole derivatives Synthesis Biological activity |
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