Encapsulation of zinc phthalocyanine into bovine serum albumin aggregates |
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| Authors: | Takanori Yokoi Shingo Hattori |
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| Affiliation: | Institute of Industrial Science, The University of Tokyo, Tokyo, Japan |
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| Abstract: | Artificial hybridization of molecules with proteins is beneficial for biomedical applications. Herein, we describe a novel method for encapsulation of zinc phthalocyanine (ZnPc) aggregates into bovine serum albumin (BSA) aggregates, but not monomeric BSA. This property is potentially useful for not only photodynamic or photothermal therapy but also development of a novel delivery system for hydrophobic drug molecules. | |
| Keywords: | Phthalocyanine bovine serum albumin aggregation photosensitizer photodynamic therapy gel-filtration chromatography |
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