First sonochemical,simple and solvent-free synthesis of chiral tert-butanesulfinimines using silica supported p-toluenesulfonic acid |
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| Authors: | Rama Moorthy Appa Jangam Lakshmidevi Sana Siva Prasad Baitinti Muralidhar Bandameeda Ramesh Naidu Manchala Narasimhulu |
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| Institution: | 1. Laboratory for Synthetic and Natural Products Chemistry, Department of Chemistry, Yogi Vemana University, Kadapa, India;2. Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, India |
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| Abstract: | A solvent-free, versatile procedure has been developed for the effective synthesis of tert-butanesulfinylimines of a variety of aldehydes using chiral tert-butanesulfinamides under green, sonochemical conditions. This method utilizes silica supported p-toluenesulfonic acid (pTSA·SiO2) as an efficient, safer and inexpensive catalyst under aerobic conditions. The practicable simplicity, easy preparation of the catalyst from readily available substances, high substrate scope, excellent yields of products in short reaction times and environmentally benign (solvent-free sonochemical) conditions are the exceptional assets of this finding. |
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| Keywords: | pTSA·SiO2 tert-butanesulfinimines aldehydes sonochemical synthesis solvent-free condition |
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