Piperazirum, a novel bioactive alkaloid from Arum palaestinum Boiss. |
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| Authors: | SK El-Desouky Young-Kyoon Kim |
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| Institution: | a College of Forest Science, Kookmin University, 861-1, Sungbuk-gu, Jungnung-dong, Seoul 136-702, South Korea
b Korea Research Institute of Chemical Technology, Taejeon 305-606, South Korea |
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| Abstract: | A novel alkylated piperazine (3α,5α-diisobutyryl-6α-isopropyl-piperazine-2-one, 1) has been isolated from the n-butanol soluble part of the leaves extract of Arum palaestinum Boiss., the chemical structure and the relative stereochemistry of 1 were elucidated on the basis of 1D and 2D NMR spectroscopic data. Piperazirum showed a significant cytotoxicity against cultured tumor cell lines in vitro. |
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| Keywords: | Arum palaestinum Araceae Cytotoxicity 3α 5α-Diisobutyryl-6α-isopropyl-piperazine-2-one NMR |
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